Title: Risk factors and therapeutic strategies of poor wound healing after the surgery for spina bifida: A large retrospective single-center cohort study of 1231 patients
Abstract:
Post-operative poor wound healing is a common but challenging matter of spina bifida. Poor wound healing presents as a delayed or stagnant process of wound healing or wound dehiscence. It may weaken the surgical effect, prolong the length of stay, aggravate the economic burden, and even induce some devastating central nervous system complications. Neurosurgeons should raise awareness of poor wound healing after the surgery for spina bifida. Identifying and managing risk factors is the most effective method to prevent poor post-operative wound healing. Previous studies have raised some relevant factors, such as wound infection, cerebrospinal fluid leakage, type of spina bifida, scoliosis and kyphosis, skin defects, age, etc. However, these conclusions are limited by the lack of stable evidence with large sample sizes and objective statistical analyses. The independent risk factors for poor post-operative wound healing in patients with spina bifida remain unclear. Furthermore, once poor wound healing occurs, management is undetermined without enough study. In this study, we answered two questions for spina bifida: what risk factors influence post-operative wound healing? How can poorly healed wounds be managed? We believe that with the largest sample size and the most evaluated characteristics, the conclusions of this study could help neurosurgeons to prevent post-operative poor wound healing of spina bifida and choose suitable treatment protocols based on the specific types of poor wound healing.
Biography:
Mengchun Sun has completed her MD at the age of 27 years from School of Medicine, Nankai University, China. And now, she is studying for her PhD in the First Medical Center of Chinese PLA General Hospital. Her major is Neurosurgery, especially about spinal cord and spine, including spinal neural tube defects, tumors, vascular malformation of spinal cord, and spinal degenerative diseases. She has published over 15 papers in reputed journals and made speeches at different academic conferences.
